12. Osteoporosis

Osteoporosis

استئوپروز، وضعیتی سیستمیک از کاهش کلی در توده یا دانسیته استخوان است که در آن تخریب استخوانی سریعتر از تشکیل آن می باشد. این عارضه که بیماری استخوان شکننده نیز نامیده می شود، فرایندی غیر قابل تغییر است که در آن استخوان ها به علت کاهش دانسیته در معرض شکستگی قرار می گیرند. میزان شیوع این عارضه یک نفر از هر ۴ زن و یک نفر از هر ۱۲ مرد می باشد، که در زنان بعد از یائسگی تا ۳۳ درصد افزایش می یابد و به...

Early effects of raloxifene on clinical vertebral fractures at 12 months in postmenopausal women with osteoporosis.

BACKGROUND Raloxifene hydrochloride therapy reduces the risk for vertebral fractures at 3 years, but the effects on clinical vertebral fractures in the first year are not known. METHODS The Multiple Outcomes of Raloxifene Evaluation (MORE) Trial enrolled 7705 women with osteoporosis, defined by prevalent vertebral fractures and/or a bone mineral density (BMD) T score at or below -2.5, who wer...

Comparison of three different osteoporosis risk assessment tools: ORAI (osteoporosis risk assessment instrument), SCORE (simple calculated osteoporosis risk estimation) and OST (osteoporosis self-assessment tool)

  Background :SCORE, OST and ORAI risk assessment tools could reduce the cost burden of BMD tests by selecting the high risk patients to osteoporosis. In this study we compared the ability of these risk assessment measures to assess probability of the osteoporosis among post-menopausal women.   Methods : 211 post-menopausal women aged 45-88 years enrolled into the study. All of the patients und...

Role of peak bone mass and bone loss in postmenopausal osteoporosis: 12 year study.

OBJECTIVE To examine the role of peak bone mass and subsequent postmenopausal bone loss in the development of osteoporosis and the reliability of identifying women at risk from one bone mass measurement and one biochemical assessment of the future bone loss. DESIGN Population based study. SETTING Outpatient clinic for research into osteoporosis. SUBJECTS 178 healthy early postmenopausal w...

Osteoporosis in Iran